Libro
Liquid Embolic System

Libro is a non-adhesive liquid embolic agent for embolization of brain Arteriovenous Malformations (AVM).


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A unique solution for pre-surgical embolization of arteriovenous malformations and Hypervascular tumors.

Libro is a non-adhesive EVOH-based liquid embolic agent for the embolization of peripheral and neurovascular Arteriovenous Malformations and Hypervascular tumors.

 

Detailed specifications

It is composed of EVOH (ethylene vinyl alcohol copolymer) with suspended micronized Tantalum powder for radiopacity and DMSO (dimethyl sulfoxide) solvent that provides complete filling and distal penetration1 of peripheral and neurovascular lesions. Its non-adhesive properties permit more distal nidus embolization without significant risk of catheter entrapment, while higher viscosities allow for controlled deployment

Libro must be injected through a DMSO-compatible microcatheter.
DMSO solvent dissipates into the blood, causing the EVOH copolymer and suspended tantalum to precipitate in situ into a spongy, coherent embolus.

Precipitation occurs in contact with an aqueous solution (eg blood, water, contrast).
It is fluid and solidifies from the outside as the solvent disperses
It transmits cohesively, forming a spongy, coherent embolus.

Provides Controlled Delivery

Slow controlled injection and delivery method
Ability to start and stop injections (pauses should not exceed 2 minutes)
Adhesive deposition and delivery
Provides the user with excellent visibility
Controlled angiography during embolic injection
Libro immediately forms a skin as the polymeric embolus solidifies from the outside to the inside, while traveling more distally in the lesion.

  • Libro is available in three product formulations, Libro (6% EVOH),
  • Libro (6.5% EVOH) and Libro (8% EVOH):
  • Libro (6% EVOH), Libro (6.5% EVOH) Recommended when feeding pedicle injections will be conducted close to the nidus.
  • LibroⓇ (8% EVOH): Recommended for embolizing higher flow and larger fistulous components.
  • Neuro Aneurysms and AVMs
  • Intracranial aneurysms, endoleaks
  • Short procedure time.
  • High power visibility
  • Micronized grain size of tantalum powder

A unique solution for pre-surgical embolization of arteriovenous malformations and Hypervascular tumors.

LibroⓇ is a non-adhesive EVOH-based liquid embolic agent for the embolization of peripheral and neurovascular Arteriovenous Malformations and Hypervascular tumors.

Order Number Product Solvent Percentage Adhesivity Volume
NR1151 Libro 18 DMSO %6.0 Non-Adhesive 1.5 cc
NR1152 Libro 20 DMSO %6.5 Non-Adhesive 1.5 cc
NR1153 Libro 34 DMSO %8.0 Non-Adhesive 1.5 cc